All of them bad.
They get drunk and burn down the Vatican.
They get drunk and reproduce.
They get drunk and drive into the ocean together.
They get sober together (and then relapse and do one of the aforementioned).
Mel adopts Brit's children.
Brit adopts Mel's accent.
They rescue one another from oblivion with an overhyped "project".
See? You CAN make this stuff up.